Written by Karen Pilkington and the CAM-Cancer Consortium.
Updated February 28, 2017

Artemisia absinthium

Does it work?

Clinical trials, case studies

No clinical trials or case studies of wormwood in humans with cancer have been published. 

Citation

Karen Pilkington, CAM-Cancer Consortium. Artemisia absinthium [online document]. http://cam-cancer.org/The-Summaries/Herbal-products/Artemisia-absinthium. February 28, 2017.

Document history

Assessed as up to date in February 2017 by Barbara Wider.
Assessed as up to date in January 2015 by Barbara Wider.
First published in May 2014 authored by Karen Pilkington.

References

  1. Natural Medicines Comprehensive Database. Absinthium (wormwood). Available at  http://naturaldatabase.therapeuticresearch.com, accessed 28th February 2017.
  2. Lachenmeier DW. Wormwood (Artemisia absinthium L.)--a curious plant with both neurotoxic and neuroprotective properties? J Ethnopharmacol. 2010 Aug 19;131(1):224-7.
  3. Judþentienë A, Mockutë D. Chemical composition of essential oils of Artemisia absinthium L. (wormwood) growing wild in Vilnius. CHEMIJA. 2004. T. 15. Nr. 4. P. 64–68.
  4. Committee on Herbal Medicinal Products. EMEA/HMPC/234463/2008: Community Herbal Monograph on Artemisia Absinthium L., Herba. European Medicines Agency 2009.
  5. Krebs S, Omer TN, Omer B. Wormwood (Artemisia absinthium) suppresses tumour necrosis factor alpha and accelerates healing in patients with Crohn's disease - A controlled clinical trial. Phytomedicine. 2010 Apr;17(5):305-9.
  6. Bora KS, Sharma A. Neuroprotective effect of Artemisia absinthium L. on focal ischemia and reperfusion-induced cerebral injury.  J Ethnopharmacol. 2010 Jun 16;129(3):403-9.
  7. Blagojevic P , Radulovic N , Palic R , Stojanovic G . Chemical composition of the essential oils of Serbian wild-growing Artemisia absinthium and Artemisia vulgaris. J Agric Food Chem . 2006 ; 54 (13); 4780-4789
  8. Lopes-Lutz D, Alviano DS, Alviano CS, Kolodziejczyk PP. Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry. 2008 May;69(8):1732-8.
  9. Krebs S, Omer TN, Omer B. Wormwood (Artemisia absinthium) suppresses tumour necrosis factor alpha and accelerates healing in patients with Crohn's disease - A controlled clinical trial. Phytomedicine. 2010 Apr;17(5):305-9.
  10. Krebs S, Omer B, Omer TN, Fliser D. Wormwood (Artemisia absinthium) for poorly responsive early-stage IgA nephropathy: a pilot uncontrolled trial. Am J Kidney Dis. 2010 Dec;56(6):1095-9.
  11. Shafi G, Hasan TN, Syed NA, Al-Hazzani AA, Alshatwi AA, Jyothi A, Munshi A. Artemisia absinthium (AA): a novel potential complementary and alternative medicine for breast cancer. Mol Biol Rep. 2012 Jul;39(7):7373-9.
  12. Wegiera M, Smolarz HD, Jedruch M, Korczak M, Koproń K. Cytotoxic effect of some medicinal plants from Asteraceae family on J-45.01 leukemic cell line--pilot study. Acta Pol Pharm. 2012 Mar-Apr;69(2):263-8.
  13. Food and Drug Administration. Dietary Supplements. Available at: https://www.fda.gov/Food/DietarySupplements/default.htm, accessed 28th February 2017. 
  14. Lachenmeier DW, Walch SG, Padosch SA, Kröner LU. Absinthe--a review. Crit Rev Food Sci Nutr. 2006;46(5):365-77.
  15. Weisbord, M.D., Jeremy B. Soule, M.D., and Paul L. Kimmel, M.D. Poison on Line — Acute Renal Failure Caused by Oil of Wormwood Purchased through the Internet. N Engl J Med 1997; 337:825-827
  16. Pelkonen O, Abass K, Wiesner J. Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment. Regul Toxicol Pharmacol. 2013 Feb;65(1):100-7.
  17. Açıkgöz SK, Açıkgöz E. Gastrointestinal bleeding secondary to interaction of Artemisia absinthium with warfarin. Drug Metabol Drug Interact. 2013;28(3):187-9.